Updated: Feb 20
Read on to hear how digital lab assistants help in one of the key steps in drug development, compound dissolution, whether performed manually or with machinery.
Using a digital lab assistant for manual compound dissolutions improves accuracy, traceability, and outcomes.
LabVoice eliminates the potential for someone to misread from the DMSO table, and provides a secondary visual confirmation.
LabVoice captures user actions in real-time, creating an audit trail where usually there would not be.
Digital lab assistants can connect to liquid handling instrumentation and offer a simple UI for error resolution and to create, run, and maintain orders.
Traditionally, compound dissolutions have been carried out by a chemist, laboratory technician, or the proper equipment. When performed manually, this process can be time-consuming, labor-intensive, and prone to errors, as it requires precise measurement and attention to detail.
Using a digital lab assistant, like LabVoice, for manual compound dissolutions improves these activities' accuracy, traceability, and outcomes.
Using the above video as an example, let's look at how LabVoice provides a better experience for the user.
Compounding technicians scan the corresponding container using the built-in barcode scanner and automatically communicate the proper DMSO calculation. Not only does this eliminate the potential for someone to misread from the DMSO table, but by placing the assistant in the scientist's line of sight, there is no need to look back and forth between a spreadsheet or computer to find those calculations.
When the solution has been created and is ready to be transferred, digital lab assistants help the compound manager complete that step. The same workflow also works with transferring existing compounds, say when moving from one phase to another. LabVoice gives the user an opportunity to correct the transferred amount if it does not match what is initially anticipated (e.g. “I pipetted 405 μL in stead of 420 μL”).Watch the video below to see a dissolution & transfer workflow:
Further examples of quality checks throughout the dissolution and transfer process include the ability to display the corresponding calculation table, providing a secondary visual confirmation. Digital lab assistants also offer quality checks, preventing users from scanning the container twice.
Lastly, the user's actions are captured in real-time by LabVoice, creating an audit trail where usually there would not be.
Of course, when liquid handling instrumentation is present, chemists and lab technicians can opt to use automation equipment.
Digital lab assistants can connect to liquid handling instrumentation and offer a simple UI to create, run, and maintain orders. Here's an example of a user creating an order on a HighRes Biosolutions workstation:
Interested in seeing LabVoice help with your compound management processes? Reach out to us at email@example.com.